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There have been reports of kidney problems, so individuals with kidney issues should use it cautiously
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Current NICE guidance (NG224) on obesity management and Technology Appraisal 875 for semaglutide recommend considering pharmacological interventions as part of a multicomponent weight management strategy
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The rate of gastrointestinal events was increased with semaglutide and there was an unexpected increase in retinopathy complications with semaglutide (vitreous haemorrhage, blindness or conditions requiring treatment with an intravitreal agent or photocoagulation)
