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Oral semaglutide (Rybelsus) achieved approximately 1013% weight loss in controlled trials, while newer oral tirzepatide formulations are showing comparable or superior results

However, healthcare professionals usually recommend weaning off semaglutide slowly to minimize spikes in hunger and weight regain

That said, both medications are FDA-approved, effective treatments for obesity and type 2 diabetes and the ideal choice depends on individual patient factors

As healthcare professionals and patients, awareness is critical

Eating small, protein-rich meals and avoiding fatty or greasy foods reduces nausea significantly in these early days

By choosing licensed clinics and pharmacies that follow state regulations