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AMG 133 demonstrated significant dose-dependent weight loss in a phase 1 randomized, double-blind, placebo-controlled clinical trial involving participants with obesity, along with an acceptable safety and tolerability profile [124]

[DOI] [PubMed] [Google Scholar] 270.Rosenstock J., et al

[DOI] [PMC free article] [PubMed] [Google Scholar] 76.Besemer F, Verschoor AJ, Diamant M, Hoogma RPLM

Post-Diagnosis Weight Gain Significantly Increases Mortality Risk The rationale for aggressive weight management in breast cancer is rooted in its prognostic impact

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"Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas"