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2018 Mar;20(3):610-619

2021;3(3) doi: 10.1016/j.jhepr.2021.100256

Like other GLP-1 receptor agonists, Exenatide extended release, sold as Bydureon BCise, works by mimicking the action of the natural hormone GLP-1

Clinical implications and relevance of microbiota modulation by GLP-1RAs Emerging clinical evidence also suggests that gut microbiota may play a mechanistic or modulatory role in the therapeutic efficacy of GLP-1 receptor agonists in T2DM, although findings remain heterogeneous across studies

However, current evidence is limited, and the proposed mechanisms and behavioral implications require empirical testing

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