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rare but serious risks include acute pancreatitis, gallbladder disease, and thyroid concerns

However, these risks were comparable in other instances with tirzepatide and controls (placebo, insulin, and GLP-1RA) in subgroup analyses according to tirzepatide dose (Table 2)

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The ominous octet, which includes 8 key pathophysiologic defects found to be present in T2D, is illustrated in Figure 1

Some plaques can rupture causing thrombosis, potentially leading to the development of acute coronary syndrome (ACS) ( 1.2 Physiology of GLP-1 Glucagon like peptide-1 (GLP-1) is a peptide hormone produced in the intestinal tract by epithelial endocrine L-cells