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New triple-acting hybrid peptides show potential as obesity therapies in knock-out mice [297]

doi: 10.1073/pnas.1513004112
While well-tolerated, they require careful consideration of potential adverse effects and contraindications (6)
Nearly a quarter of cannabis users who meet the DSM-5 (the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition) criteria for CUD have a severe disorder that interferes with their everyday life [6]

More recently, data from these studies and the Danish MetaHIT project were analysed after controlling for metformin treatment [84]