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, Suppression of food intake by Glp1r/Lepr-coexpressing neurons prevents obesity in mouse models

When combined with medicines such as metformin or insulin, there is a theoretical risk of hypoglycaemia (low blood sugar), and close monitoring would be required

Sleeve gastrectomy alters the gastroesophageal anatomy, increasing intragastric pressure, which in turn exacerbates acid reflux and promotes chronic oesophageal inflammation [193]