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A secondary mechanistic analysis of the SUMMIT trial found associations between tirzepatide treatment and reductions in circulatory volume and markers of cardiac injury [85]

Results GLP-1RAs alleviate RA progression by suppressing synovial inflammation and cartilage destruction Recent studies have demonstrated that GLP-1RAs not only exert significant metabolic effects in the management of diabetes and obesity, but also possess anti-inflammatory properties [33]

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