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GLP-1assisted weight loss offers a different approach

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The Expression of GLP-1 Receptor mRNA and Protein Allows the Effect of GLP-1 on Glucose Metabolism in the Human Hypothalamus and Brainstem

The first is a resolution of NASH or steatohepatitis, and the second is an improvement of fibrosis stage

second, the knockdown of SESN2 leads to a reduction in the translocation of p62 to the mitochondria and decreases its phosphorylation level at critical sites (such as Ser403), which is necessary for the encapsulation of the mitochondria by autophagosomes