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Tirzepatide vs Insulin: The CFB in eGFR was comparable with all doses of tirzepatide vs insulin [for tirzepatide 5 mg: MD 0.36 mL/min/1.73 m 2 (-1.41, 2.14), I 2 = 82%, P = 0.69, very low certainty of the evidence

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The typical starting dose is 2.5 mg once weekly for four weeks

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