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(2020, March)

Maybe these meds have been a nightmare and youre feeling more confused than ever

The CVOT of oral semaglutide in people with type 2 diabetes and established CVD, chronic kidney disease (CKD) or both demonstrated a significant reduction in MACE compared with placebo (McGuire et al, 2025)

Interesing post Maam, This represents a fundamental shift in GLP-1 therapeutics---transitioning from complex biologics to scalable small molecules like Orforglipron with clear implications for cost, access, and global supply Interesting Great & Useful Initiative mem

Metabolism and genetics Individual variations in GLP-1 receptor density and sensitivity affect how strongly any given dose activates the appetite suppression and glucose regulation pathways

Cell Stem Cell