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GLP-1 GIP NASH Trial NEJM 2024 View on PubMed 2023 Diabetes Care Mechanism Glucagon Co-Agonism Amplifies GLP-1-Mediated Weight Loss via Brown Adipose Thermogenesis Finding: In mouse models, adding glucagon receptor agonism to GLP-1R agonism increased brown adipose tissue thermogenic gene expression (UCP1 +62%, PGC-1 +44%) and significantly amplified fat oxidation (+38%)
Regular check-ins and monitoring will ensure that you are on track and address any questions or concerns that arise
Tip: Eat 46 small meals rather than 23 large ones
You can always eat more if youre still hungry
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