can you take a break from glp 1 GLP-1 Receptor Agonists A Practical Guide to GLP-1

Glucagon-like peptide-1 (GLP-1) and glucose dependent insulinotropic polypeptide (GIP) are the two main incretins and are secreted by enteroendocrine L- and K-cells, respectively

If approved for treatment, your provider will: Regular monitoring is essentialand in some states, legally required: States like Florida mandate follow-ups at least every 3 months, while Virginia requires a check-in within 30 days of starting treatment

Moreover, GLP-1RAs can alleviate vascular remodeling expressed as neointimal hyperplasia after induced vascular injury

Zambrowicz B, Ogbaa I, Frazier K, Banks P, Turnage A, Freiman J, Boehm KA, Ruff D, Powell D, Sands A

Patients with a history of heart attack or stroke may particularly benefit from weight loss through GLP-1 therapy, as weight reduction independently reduces cardiac event risk

Interestingly, GLP-1/GIP coagonists have also been reported to have weight and glucose-lowering effects in obese T2D patients despite numerous studies supporting the notion that GIP promotes weight gain/obesity