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why does retatrutide cause diarrhea Side Effects: What Patients Should Know Retatrutide diarrhea: why it happens
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Choice of the second agent to start alongside metformin should be based on the individual's priorities, preferences, and comorbidities [Grade D, Consensus]

Jastreboff, et al., 'Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial conducted in the USA', Lancet , vol

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Please keep in mind that clinical studies of both GLP-1 and GLP branded medications show weight loss in subjects that were receiving the medication for an average of 3 to 6 months at a minimum

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