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doi: 10.1007/s40618-015-0404-6 29 HabibZAHavstadSLWellsKDivineGPladevallMWilliamsLK
Hayden, M
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La vida media biolgica del GLP-1 in vivo es corta (aproximadamente 2 minutos) y se degrada rpidamente por la accin de la enzima dipeptidil dipeptidasa-4 (DPP-4) 21 , por tanto, el enfoque farmacolgico ha sido dirigido a prolongar la vida media del GLP-1, ya sea por modificacin estructural del pptido original o por inhibicin de la enzima DDP-4
L., Fujioka, K., Plodkowski, R
Cyclosporin is an oral cyclic peptide drug which prompted chemists to wonder whether insulin could be made into a cyclic peptide
