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This is referred to as first-line therapy because metformin is safe, affordable, and has been proven effective through decades of research

Breakthrough technologies may be required to achieve bioavailability sufficient for therapeutic efficacy

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Drug Metab Rev

Jr., Kwan, A

A recent study shows people with obesity taking GLP-1 drugs are 20% less likely to suffer a cardiovascular event, and studies are under way for their use to treat the liver disease non-alcoholic steatohepatitis, as well as the neurodegenerative conditions Parkinsons and Alzheimers