glp-1 news today october 23 2025 Perspectives from employers on the costs and issues associated with covering GLP-1 agonists for weight loss Should Psychiatrists Prescribe GLP-1 Medications?
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In someone who doesnt have diabetes, the medicine attaches to their pancreas, but they dont really need any more insulin so it doesnt release anymore insulin

Driessen et al
GLP-1 receptor agonists on their own have a low risk of hypoglycemia because they work in a glucose-dependent way they stop boosting insulin once blood sugar normalizes
Hair thinning has been reported in weight-management trials of semaglutide [10] and is discussed with tirzepatide too

Gibbons et al., studied the effect of oral semaglutide in 15 subjects with type 2 diabetes and reduction on appetite and craving, demonstrating not just the reduction in calorie intake, but also lowering the palatability and preference for sweet and high fat food (177)

To date, 18 CVOTs have been published for these newer GLDs (Fig