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What You Need to Know A clinical review of the 2025 FDA crackdown on compounding pharmacies

It is classified as a dietary supplement in the United States rather than a prescription medication and is not FDA-approved for glycemic control or recommended by the American Diabetes Association as standard therapy for diabetes

however, our search did not recall any such trials related to the topic [15]

Gliptins may represent a valuable alternative to a sulfonylurea or a glitazone after failure of monotherapy with metformin while GLP-1 receptor agonists may be considered as a good alternative to insulin (especially in obese patients) after failure of a dual oral therapy

Recently, these GLP-1 agonists have made their way into the marketplace as miracle weight loss drugs because they suppress appetite and slow gastric emptying , which helps prolong the sense of fullness after a meal and makes it easier to remain in a significant caloric deficit

In June 2025, the European Medicines Agency (EMA) formally concluded that semaglutide-containing medications, including Ozempic, Wegovy, and Rybelsus, may cause rare but serious cases of NAION