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How Phentermine Works: Sympathomimetic vs

Patients taking tirzepatide 10 mg achieved an average of 19.5% weight loss, and patients taking tirzepatide 15 mg achieved an average of 20.9% weight loss

Xu, Y., et al., 2021

The trial enrolled 338 adults with obesity (BMI 30) or overweight with comorbidities (BMI 27) and ran for 48 weeks
A patch that delivers only 1030% of the dose needed creates a subtherapeutic effect, leaving patients hungry and without the metabolic benefits of higher doses

Several novel compounds and combination therapies are undergoing clinical trials, targeting different metabolic pathways to enhance efficacy and safety