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Topiramate (Topamax) Topiramate (50400 mg per day) produces more weight loss than metformin, averaging about 4 kg (Goh KK et al, Int J Psychiatry Clin Pract 2019;23(1):1432)

The US Food and Drug Administration (FDA) put various forms on the official shortage list, allowing compounding pharmacies to formulate their own versions

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doi:10.1038/sj.ijo.0802439 41

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