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Introduction Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) are key therapies for type 2 diabetes and obesity, regulating blood glucose by mimicking endogenous GLP-1

Retatrutide, a not endogenously occurring peptide, stimulated the glucagon receptor (GCGR), the glucose-dependent insulinotropic polypeptide (GIP) receptor (GIPR), and the glucagon-like peptide-1 receptor (GLP-1R) in cell cultures

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GLP-1 is the hormone our body makes to help reduce hunger and cravings after and in-between meals
New research suggests GLP-1 drugs may lower the risk of certain cancers, but could also raise the likelihood of developing kidney cancer.
