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Several large studies have shown positive results for people with kidney disease: The LEADER Trial: A medication called liraglutide lowered the risk of kidney problems by 22%4

However, cotadutide demonstrated superior performance in decreasing liver triglyceride levels and ameliorating mitochondrial functional markers in the liver compared to liraglutide, despite comparable reductions in body weight and food intake between the two treatments [43]

However, a significant effect on major kidney outcomes was not observed (HR 0.91, 95% CI 0.801.05)

As dosages increased, so did the negative effects

Intriguingly, Sisley et al

Zhang Y, Ling Y, Yang L, Cheng Y, Yang P, Song X, et al