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Regarding pharmacodynamics, TZP appears as a biased GLP-1R-GIPR co-agonist, because of its positive effects on cAMP generation over -arrestin recruitment, which is conversely stimulated by GLP-1R

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[DOI] [PubMed] [Google Scholar] 38.Schirra J., Nicolaus M., Roggel R., Katschinski M., Storr M., Woerle H.J., Gke B

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