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More recently, the FLOW trial with semaglutide in people with type 2 diabetes and CKD the first randomised controlled trial with a dedicated renal outcome for GLP-1 RAs was reported (Perkovic et al, 2024)

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FDA-Approved Tirzepatide Dosing: What the Label Says The FDA-approved tirzepatide dosing schedule begins at 2.5mg weekly and escalates by 2.5mg increments every four weeks until reaching the 15mg maintenance dose

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He said: "These are the most powerful glucose-lowering drugs on the planetthey are more effective at getting the average glucose lower than even insulin, in the setting of Type 2 diabetes