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Combining it with another GLP-1 or GIP agonist (semaglutide, tirzepatide) would compound the same receptor load and the same GI and hypoglycemia risks with no efficacy evidence to support it

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The standard protocol in clinical trials escalated doses every 4 weeks

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Oral semaglutide is a GLP-1 medicine in tablet form

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The niacinamide simply comes along for the ride at whatever concentration the new compound provides

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