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In patients with T2DM, where islet neogenesis and -cell replication are normal, increased apoptosis is the main cause of the decrease in their -cell numbers, so preventing -cell apoptosis may become an effective means of treating T2DM ( GLP-1 has a beneficial effect on -cell function by promoting -cell proliferation and neogenesis and reducing apoptosis (Zheng et al., 2022)

Then theres the maintenance angle

Weight loss may alter relationship dynamics, and partners may respond differently to physical changes

GLP-1 medications are therapies that replicate the function of the glucagon-like peptide-1 hormone, which is crucial for appetite regulation and glucose metabolism

Rotating injection sites and proper technique can minimise these effects

Jeffrey Lee, MD, a double board-certified plastic surgeon and founder of JL Plastic Surgery in Boston, MA, who was not involved in the study, spoke to Healthline about these hidden side effects, why they may occur, and what people may misunderstand about GLP-1s from social media posts