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More complicated molecular modifications that led to the approval of once-weekly products include fusing either recombinant human serum albumin (Tanzeum) or an antibody fragment crystallizable (Fc) moiety (Trulicity) to a GLP-1 analog

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[DOI] [PMC free article] [PubMed] [Google Scholar] 47.Frankel DS, Vasan RS, DAgostino RB, Sr, et al

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MOTS-C is a mitochondria-derived peptide that activates AMPK your body's energy sensor
