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After noticing about half of users stop taking GLP-1s shortly after starting treatment, Al-Aly wanted to understand the consequences of discontinuing GLP-1 medications on cardiovascular health, particularly the risk of major adverse cardiovascular events, including heart attack, stroke and death

This showed us that GLP-1 and GIP are not as effective in shutting down glucagon and stimulating insulin secretion in patients with kidney disease compared to controls, suggesting increased resistance to their action in CKD, Ahmadi added

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Liraglutide-treated patients had also a lower risk of death from cardiovascular causes and from any cause [32]