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doi: 10.3389/fimmu.2021.714177 [DOI] [PMC free article] [PubMed] [Google Scholar] 7

Individuals have a higher risk of gaining the weight back if they do not keep up with the healthy lifestyle changes they made

Patients consistently had improved glycemic levels and multiple drugs, such as tirzepatide alone or semaglutide in combination with cagrilinitide, were highly effective at promoting weight management

Retatrutides engineering allows it to bind uniquely to these receptors [34]

doi: 10.1007/s00384-023-04456-z 77 WalugaM

Especially regarding the central nervous system, the expression of GLP-1 receptors in reward-related regions, such as the hypothalamus, amygdala, nucleus accumbens, paraventricular nucleus, ventral tegmental area, locus coeruleus, and brain stem [21] may suggest a possible association between reward learning and symptoms like anhedonia in diseases such as depression