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Additionally, GLP-1 activation affects blood vessel tone and serotonin pathways in the brain, both known to influence headache frequency

Correspondent Tracy Smith talks with experts who say the drugs might prove useful in treating other diseases associated with obesity (including cancer)

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paraventricular nucleus of the hypothalamus, dorsomedial hypothalamus, lateral hypothalamus and arcuate nucleus) 57,58,59

Here is the important context: Most berberine research involves oral supplementation at doses typically ranging from 500mg to 1500mg daily

[DOI] [PMC free article] [PubMed] [Google Scholar] 155.Aronne LJ, et al