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Cognition improved in exenatide treated patients in fluid intelligence (baseline 38.4 (8.2), 12 weeks 52.9 (6.6), p=0.0005), processing speed (baseline 43.7 (9.4), 12 weeks 58.4 (10.4), p=0.0058) and episodic memory (baseline 49.4 (5.3), 12 weeks 62.1 (13.2), p=0.0315)

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DPP IV was chosen as a template to employ molecular docking via Discovery Studio to search for natural phenolic compounds whether they have the inhibitory function of DPP IV