glp 1 agonists mechanism of action of GLP-1 [25] How do GLP-1 Agonists Work?

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Both animal and human studies have shown that increased GLP-1 activity reduces intestinal motility [23]

The same group showed that GLP-1 continued to suppress lipogenesis and increase lipolysis in day 14 differentiated cells from subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT), with the effects being more pronounced in SAT [31]

Reid CT, Tobin AM, Ahern T, OShea D, Kirby B

Finally, neither trial looked at lifestyle alternatives like adjusting diet and exercise

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