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Health markers improving, blood pressure, blood sugar, cholesterol, all trending in the right direction

It should be used cautiously or avoided in patients with a history of pancreatitis, severe gastrointestinal disease (e.g., gastroparesis), or gallbladder disease

In the head-to-head comparison between tirzepatide and semaglutide, the two drugs yielded similar risks for component endpoints all-cause mortality (HR 1.03, 95% CI 0.84 to 1.27), myocardial infarction (HR 1.03, 95% CI 0.88 to 1.21) and stroke (HR 1.15, 95% CI 0.92 to 1.45) (Fig

Panel a : The percentage of participants reaching weight-reduction thresholds at Week 48 is based on logistic regression with multiple imputation using a treatment-regimen estimand

systolic blood pressure down 6-9 mmHg, reversing on withdrawal: Sattar Ann Rheum Dis 2026

Patients feeling nauseated or fatigued may decrease their usual exercise routines, leading to deconditioning