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In patients with elevated cancer risk, particularly gastrointestinal malignancies, semaglutides protective associations may warrant further investigation beyond its established metabolic effects

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These can include personal or family history of medullary thyroid carcinoma, Multiple Endocrine Neoplasia syndrome type 2, history of pancreatitis, certain kidney or gallbladder conditions, pregnancy or breastfeeding, and other individual health factors

Higher doses (25 mg, 50 mg) have been studied for weight loss and may offer similar results to the Wegovy 2.4 mg dose