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These combined factorshigh dropout rates, early plateaus, and widespread patient frustrationhighlight the limitations of behavioral therapy alone and suggest that earlier pharmacological intervention might provide more effective and humane treatment for individuals struggling with obesity

In this narrative literature review, we explore the pharmacological properties of tirzepatide and critically summarize and comment on the results of the clinical studies conducted thus far, as well as discuss the potential implications for the treatment of obesity, T2DM, and associated cardiometabolic complications

During this time, you cannot start treatment

Nachnani JS, Bulchandani DG, Nookala A, Herndon B, Molteni A, Pandya P, Taylor R, Quinn T, Weide L, Alba LM

Clearly, these observations must be taken into account when prescribing DDP-4is, always with a view to a targeted therapy that is increasingly designed to meet the specific needs of the individual patient

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