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Hepatic-portal vein infusions of glucagon-like peptide-1 reduce meal size and increase c-Fos expression in the nucleus tractus solitarii, area postrema and central nucleus of the amygdala in rats

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Essential listening for anyone navigating GLP-1 maintenance, obesity medicine, and sustainable weight management

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Drug interactions can impact the effectiveness of semaglutide and other medications you may be taking

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For patients who are appropriate surgical candidates but want to exhaust pharmacologic options first, or who are not surgical candidates due to comorbidities, tirzepatide represents the closest approximation of surgical efficacy in a pharmacologic option currently available

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Ongoing assessment Dose adjustments, substitutions, and/or addition of other antihyperglycemic medications should be made in order to reach the target A1C within 3 to 6 months [Grade D, Consensus]

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The thigh can also be used, particularly the front and outer areas

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