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It is documented that GLP-1 treatment induces a significant increase in PGC-1 expression via the cAMP/PKA/CREB axis (Kang et al., 2006, 2015

doi: 10.1016/j.expneurol.2011.06.005 [DOI] [PMC free article] [PubMed] [Google Scholar] 173.Morris JK, Bomhoff GL, Stanford JA, Geiger PC

Still, even modest improvements can give your body the reset it needs to support weight loss

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A weight loss plateau is defined as a period where weight loss stalls or stops, despite continuing the medication and maintaining lifestyle efforts like diet and exercise