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In the STEP UP phase 3 trial, Wegovy HD achieved an average weight loss of 20.7% over 72 weeks compared to 17.5% for the 2.4 mg dose and 15% seen in the original STEP 1 trial
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The trade-off is higher cost but potentially more complete formulations tailored to specific research goals
This includes measurement of serum creatinine and calculation of eGFR to establish a baseline for monitoring throughout treatment
