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Side effects were mild or moderate, occurring primarily during dose escalation

Regulate your blood sugar with guidance from our top endocrinologists

You should contact your GP if you experience: Absence of periods for three consecutive cycles (amenorrhoea) if you previously had regular menstruation Unusually heavy bleeding (soaking through a pad or tampon every hour for several consecutive hours) or passing large clots Bleeding between periods or after intercourse, which requires investigation regardless of medication use Severe pelvic pain that differs from typical menstrual cramping Symptoms of anaemia including persistent fatigue, breathlessness, palpitations, or pallor Seek urgent medical help via NHS 111 or A&E for very heavy bleeding with dizziness or fainting, or severe abdominal pain that could indicate complications such as pancreatitis

These effects are supported by extensive clinical research showing meaningful weight reduction over sustained treatment periods when paired with appropriate medical oversight

[15] [16] It is worth noting that these energy improvements typically develop gradually over weeks to months as metabolic changes occur, rather than immediately after starting treatment

Signs include: running a high fever, skin hot to the touch excessive sweating or dry skin that doesnt sweat muscle cramps rapid pulse or heart rate low blood pressure disorientation irrational or erratic behavior dizziness headache nausea or vomiting dry mouth and intense thirst physical collapse coma Thompson: Extreme heat can also damage the medication and alter the properties of the proteins