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Our study indicates ER36 not only as a prognosis biomarker for breast cancer but also as a potential therapeutic target

This requirement of ECL1 recognition drives the above six key positions in dual or triple agonists (tirzepatide, peptide 20 (MAR423), and retatrutide) to use amino acids similar to those in GLP-1/GCG, while the other positions in the middle region show considerable variability (Fig

Estrogen levels affect the gut microbiome and may cause higher levels of gut permeability

Instead, it follows a specific titration schedulea process of gradually increasing the dose over several months

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