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Biochemical and Biophysical Research Communications Endogenous GLP-1 acts on paraventricular nucleus to suppress feeding : Projection from nucleus tractus solitarius and activation of corticotropin-releasing hormone, nesfatin-1 and oxytocin neurons

The retatrutide dosing schedule follows a similar gradual titration approach designed to minimize exactly these kinds of side effects

Individuals with higher external eating scores at the start of the study tended to show greater weight loss

PMID: 25707779