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All authors contributed to the interpretation of findings, provided critical revision of the manuscript for important intellectual content, and approved the final version for publication

For individuals with well-controlled hypothyroidism on stable levothyroxine treatment, there is generally no contraindication to using Wegovy

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Methionine, a sulfur-containing, essential amino acid, is a precursor of S-adenosylmethionine, a cofactor for one-carbon metabolism and the final methyl donor for the methylation of DNA, RNA, proteins, and phospholipids.The methionine synthase plays a paramount role in the synthesis of nitrogenous bases (purines and pyrimidines) involved in the formation of DNA

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