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Unlike FDA-approved medications (e.g., Wegovy, Ozempic, Zepbound), compounded alternatives lack agency review for safety, quality, and efficacy

An albumin engineering strategy (QMP) compensates for the poor PK properties resulting from cleavage, as demonstrated for a GLP-1 albumin fusion

Alhazmi A & le Roux CW

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De Giorgi and colleagues present a comprehensive analysis of pre-clinical and clinical studies examining the role of glucagon-like peptide-1 receptor agonists in mental disorders.