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GLP-1 receptor agonists mimic the natural gut hormone GLP-1 to improve insulin release, lower blood sugar, reduce appetite, support weight loss, and decrease inflammation throughout the body. Which conditions can GLP-1 medications help

Therefore, meals and snacks with a good balance of protein and fiber are key to increasing GLP-1 naturally but also experiencing increased satiety and satisfaction

Lancet (2014) 384:134957

References: Baggio LL, Drucker DJ (2007): Biology of incretins: GLP-1 and GIP

In North Carolina, the state employee health plan initiated coverage of GLP-1s for weight loss purposes in 2015

This balancing act was attempted by Novo Nordisk, when they developed a triple agonist , compound 16, which in mice was able to reduce body weight by an average of around 30%, fat mass by around 55% and lean mass by around 10% after 27 days [33]