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Contact your GP if you experience persistent reflux despite lifestyle changes, difficulty swallowing, unintentional weight loss, persistent vomiting, or signs of gastrointestinal bleeding such as black stools or vomiting blood
Compounding pharmacies typically recommend discarding multi-dose vials after 28 days of first use, even if medication remains

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Space other oral medications 30+ minutes apart from melatonin if possible, though this is not a strict requirement

GLP-1s can decrease the frequency and strength of gallbladder contractions
