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This is particularly important when one of the components has a narrow therapeutic window

The advent of oral formulations, including semaglutide and ofrutide, has further enhanced patient adherence

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9 , 29 , 30 , 31 In observational studies based on European and American study populations, however, the reported rates of discontinuation and addon therapy were much higher than reported in the randomized clinical trials

[Google Scholar] 16.Igelstrm E, Campbell M, Craig P, Katikireddi SV