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Nausea was more frequent with tirzepatide vs placebo, especially with tirzepatide 15 mg (OR 5.60 [95% CI 3.12, 10.06]), associated with higher incidence of vomiting (OR 5.50 [95% CI 2.40, 12.59]) and diarrhoea (OR 3.31 [95% CI 1.40, 7.85])

Klein C, Westenberger A

The authors declare that they did not use any type of generative artificial intelligence for the writing of this manuscript.

Gorgojo-Martnez JJ et al

Finally, differences in how studies reported side effects and treatment adherence make it harder to draw firm conclusions

NICE guidance recommends annual diabetic eye screening for all people with diabetes, with the frequency of ophthalmological review potentially adjusted based on individual clinical factors such as existing retinopathy and anticipated speed of glycaemic improvement