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[DOI] [PMC free article] [PubMed] [Google Scholar] 111.Benetti E., Mastrocola R., Vitarelli G., Cutrin J.C., Nigro D., Chiazza F., Mayoux E., Collino M., Fantozzi R

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Commonly reported side effects include: Nausea and vomiting Diarrhoea or constipation Decreased appetite (which may be pronounced) Abdominal discomfort or bloating Injection site reactions (redness, bruising, or mild pain) Increased heart rate (a recognised class effect) In clinical trials, the majority of gastrointestinal side effects were described as mild to moderate in severity and tended to resolve over time as the body adjusted to the medication

You can read the full article at LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept: Cell Metabolism

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These are rare but serious potential complications documented in clinical trials