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The obtained results provide a rationale for conducting phase III studies to evaluate the longer-term effects and safety of semaglutide in pill version

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H., & Mark, R

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Researchers have documented the safety profile observed in published Phase 2 research as predominantly gastrointestinal effects (nausea, diarrhoea, vomiting) typical of the incretin class, occurring most prominently during dose escalation and tending to decline with continued exposure (PMID 39515565, PMID 41785010)