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The degree of weight loss varies by medication and dose

doi: 10.1097/MCO.0000000000000468 103 RyanP
This selection may also have influenced the observed adverse event rates, as treatment tolerability and physician familiarity with specific agents may have varied over time, potentially affecting both reporting and management of side effects

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Furthermore, the initial phase of rapid weight loss often coincides with the period when side effects like nausea or fatigue might be most pronounced 31 , potentially hindering a person's ability to start or maintain consistent strength training and ensure adequate protein intakethe very strategies needed to protect muscle

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